616.234.5000

Metabolomics and Bioenergetics Core

Van Andel Institute’s Metabolomics and Bioenergetics Core enables scientists to investigate the metabolic mechanisms of disease through state-of-the-art respirometry, metabolite profiling, stable isotope tracing and untargeted analysis.

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Recent Publications

Sheldon RD, Ma EH, DeCamp LM, Williams KS, Jones RG. 2021. Interrogating in vivo T-cell metabolism in mice using stable isotope labeling metabolomic and rapid cell sorting. Nat Proto.

Izreig S, Gariepy A, Kaymak I, Bridges HR, Donayo AO, Bridon G, DeCamp LM, Kitchen-Goosen SM, Avizonis D, Sheldon RD, Laister R, Minden MD, Johnson NA, Duchaine TF, Rudoltz MS, Yoo S, Pollak MN, Williams KS, Jones RG. 2020. Repression of LKB1 by miR-17~92 sensitizes MYC-dependent lymphoma to biguanide treatment. Cell Rep Med.

Roy DG*, Chen J*, Mamane V, Ma EH, Muhire BM, Sheldon RD, Shorstova T, Koning R, Johnson RM, Esaulova E, Williams KS, Hayes S, Steadman M, Samborska B, Swain A, Daigneault A, Chubukov V, Roddy TP, Foulkes W, Pospisilik JA, Dourgeois-Daigneualt, Artyomov MN, Witcher M, Krawczyk CM, Larochelle C, Jones RG. 2020. Methionine metabolism shapes helper T helper cell responses through regulation of epigenetic reprogrammingCell Metab 31(2):250–266. 
*Co-first authors
Highlighted in a preview in Cell Metabolism

Contact Us

Ryan Sheldon, Ph.D.
Core Manager
616.234.5727
Ryan.Sheldon@vai.org